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Following in vitro tests, compound 57 (Figure 7) was shown to be the most potent DPP-4 inhibitor, with an IC 50 of 0.87 nM

It is well-tolerated by most people, and it does not interact with other medications

The authors concluded that intra-articular BPC 157 injection could be a promising treatment option for patients with various types of knee pain, including osteoarthritis, patellar tendonitis, and meniscal tears

Concentrations of 0.1% to 1% are well-supported by trial data